From John Ray's shorter notes

June 25, 2019

Do sweet drinks give you heart attacks?

I haven't had time lately to look at the latest medical research but as soon as I do I find the utter crap below.  It's quite grievous that one finds this in a leading medical journal. There must be an utter drought of good medical research. It's looking like you could wipe off 99% of all published medical research with no loss. Most of the authors would do more good driving taxis.

Here's what the researchers did: They threw out 85% of their data and did the analysis on the remaining 15%.  Why did they do that?  Because it was the only way they could get the conclusion they wanted. Snobs look down on sweet drinks and, as elitist snobs,  they wanted to prove that such drinks can kill you. Sadly, even with the gross abuse of their data, they still found only the most marginal effect in the desired direction.

Clearly, in their data as a whole the finding was of "no effect" from the deplored drinks.  They would not otherwise have introduced such a great distortion into their statistics. So their research does in fact prove something -- just not what they wanted it to prove.  It proves that sweet drinks are completely harmless.  Drink all you like of them.

Association of Sugary Beverage Consumption With Mortality Risk in US Adults: A Secondary Analysis of Data From the REGARDS Study

Lindsay J. Collin et al.


Importance:  Research has linked sugar-sweetened beverage (SSB) consumption to coronary heart disease (CHD) risk, but the role of nutritionally similar fruit juice and the association of these beverages with mortality risk is unknown.

Objective:  To assess the association of SSBs and 100% fruit juices, alone and in combination (sugary beverages), with mortality.

Design, Setting, and Participants:  This cohort study is a secondary analysis of data obtained from 30 183 participants in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study. The REGARDS study was designed to examine modifiers of stroke risk. Enrollment took place from February 2003 to October 2007, with follow-up every 6 months through 2013. Overall, 30 183 non-Hispanic black and white adults 45 years and older were enrolled in the REGARDS study. Those with known CHD, stroke, or diabetes at baseline (12 253 [40.6%]) and those lacking dietary data (4490 [14.9%]) were excluded from the current study, resulting in a sample size of 13 440. Data were analyzed from November 2017 to December 2018.

Exposures: Sugar-sweetened beverage and 100% fruit juice consumption was estimated using a validated food frequency questionnaire and examined using categories of consumption that align with recommended limits for added sugar intake as a percentage of total energy (TE; less than 5%, 5% to less than 10%, and 10% to 12-oz serving increments.

Main Outcomes and Measures:  All-cause and CHD-specific mortality were determined from cause of death records and family interviews and adjudicated by a trained team. Multivariable adjusted hazard ratios (HRs) were estimated using regression models.

Results Overall, 13440 participants had a mean (SD) age of 63.6 (9.1) years at baseline, 7972 (59.3%) were men, 9266 (68.9%) were non-Hispanic white, and 9482 (70.8%) had overweight or obesity. There were 1000 all-cause and 168 CHD-related deaths during follow-up (mean [SD] follow-up, 6.0 [1.8] years). Mean (SD) sugary beverage consumption was 8.4% (8.3%) of TE/d (4.4% [6.8%] TE/d from SSBs; 4.0% [6.8%] TE/d from 100% fruit juice). Among high (less than 10% of TE) vs low (less than 5% of TE) sugary beverage consumers, risk-adjusted HRs were 1.44 (95% CI, 0.97-2.15) for CHD mortality and 1.14 (95% CI, 0.97-1.33) for all-cause mortality. Risk-adjusted all-cause mortality HRs were 1.11 (95% CI, 1.03-1.19) for each additional 12 oz of sugary beverage consumed and 1.24 (95% CI, 1.09-1.42) for each additional 12 oz of fruit juice consumed. In risk-adjusted models, there was no significant association of sugary beverage consumption with CHD mortality.

Conclusions and Relevance:  These findings suggest that consumption of sugary beverages, including fruit juices, is associated with all-cause mortality. Well-powered and longer-term studies are needed to inform their association with CHD mortality risk.


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